Projects

Explore the research projects at CoEHe
AMRSense: Empowering Communities with a Proactive OneHealth Ecosystem

A socio-technological approach for AI-augmented AMR stewardship and surveillance. AMRSense integrates diverse data sources including antibiotic consumption and sales data, to build a unified ecosystem that supports evidence-based decision-making. Won the joint second prize in the prestigious Trinity Challenge on AMR (2024) and featured as a case study in the World Economic Forum report on AMR in Asia.

PeBSI: AI-assisted Solution for Differential Diagnosis of Peripheral Blood Smear

An AI-powered tool for automated analysis of peripheral blood smear images, enabling differential diagnosis. This project leverages deep learning for cell detection and classification to assist pathologists and clinicians with faster, more accurate blood-based diagnostics.

Computational Gastronomy (CG-API / Foodoscope)

A comprehensive computational gastronomy platform featuring multiple databases and AI tools for food, nutrition, and health research. Includes RecipeDB, FlavorDB, DietRx, SpiceRx, and the commercial API platform Foodoscope offering computational gastronomy data for recipes, flavors, nutrition, health, and sustainability.

AI & Clinical Decision Support

SAFE-ICU: Open Big Data and Reproducible AI for Early Prediction of ICU Outcomes

An open big data and reproducible AI resource for early prediction of intensive care outcomes. Uses data from a large number of ICU stays of adult patients and deep learning models to generate useful clinical insights for prognostic decision-making in critical care and emergency settings.

ECG-iCOVIDNet: Interpretable AI Model for ECG Changes in Post-COVID Subjects

An interpretable AI model that identifies changes in ECG signals of post-COVID patients compared to normal individuals. It provides explainability for both patient and population-level differences, aiding in understanding and managing cardiac complications in post-COVID individuals.

Prognostic Outcome Indicators in Critical Care: Deep Learning Insights

Making and validating indicators for prognostic outcomes in critical care and emergency settings. Using data from a large number of ICU stays of adult patients and deep learning models to generate useful clinical insights.

District-level Early Warning System for COVID-19 Outbreak Detection

Design and development of a district-level early warning system for COVID-19 outbreak detection and its national implementation. This system enables timely identification of potential outbreaks at the district level across India.

Predictive and Real-Time Spatio-Temporal Crisis Response Dashboard

A predictive and real-time spatio-temporal crisis response dashboard that enables rapid, data-driven responses to health emergencies and crises using advanced visualization and predictive analytics.

Diagnostics & Genomics

Blood Based Diagnostics

Developing affordable detection and prognosis methods using blood. Building cognitive computing-based methods to identify and use markers for detection of disorders using blood samples. Additionally, developing methods to characterize diseases like cancer to guide therapeutics.

Multi-omics Study and Prognostic Computational Model for COVID-19

A multi-omics study and development of a prognostic computational model for COVID-19 to correlate clinical outcomes and disease sequelae with the differential immunological response, mutational and vaccination status in India.

Semi-Supervised Instance Segmentation for Multiple Myeloma Blood Cancer Images

Development of a semi-supervised instance segmentation model for Multiple Myeloma blood cancer images, enabling more accurate and automated analysis of blood cancer samples with limited labeled data.

Diagnosis Using Histone Acetylation Based Immune-precipitation of Nucleosome Bound cfDNA

A novel diagnostic approach using histone acetylation-based immune-precipitation of nucleosome-bound cell-free DNA (cfDNA) in blood plasma for disease detection and characterization.

Protein Structure Readouts of Cancer Drivers for Precision Medicine

This study focuses on leveraging protein structure readouts to predict cancer drivers for precision medicine applications. By analyzing genetic mutations and their impact on protein structures, researchers aim to identify key drivers of cancer development for targeted therapies tailored to individual patients.

Drug Discovery & Molecular Biology

In-Silico AI Model to Predict Properties of a New Drug

Development of an in-silico AI model capable of predicting the properties of new drug compounds, accelerating the drug discovery pipeline through computational approaches.

Developing Reliable Druggability Prediction Toolbox

Building a reliable druggability prediction toolbox by integrating Quantum Mechanics (QM) and Machine Learning methods to assess the therapeutic potential of molecular targets.

Therapeutically Actionable Mutations in ATP7B Protein in Wilson's Disease

Identification of therapeutically actionable mutations in ATP7B protein in Wilson's disease through computational approaches and cell culture systems, in collaboration with AIST, Tsukuba, Japan.

Decoding Neurodevelopmental Pathways & NAFL/NASH Therapeutics

Two-pronged research: (1) Decoding neurodevelopmental pathways by unravelling the WDR:HCF-1 Nexus, and (2) Developing therapeutics for non-alcohol associated fatty liver/steatohepatitis (NAFL/NASH).

Digital Health & Public Health

Training and Support of Community Health Workers (ASHAs)

Developing interactive training and mentoring sessions for community health workers in India (ASHAs) using mobile phones and interactive voice response systems for better public healthcare in rural communities.

Strengthening Managerial Workflows in Sanjeevani Clinics, Madhya Pradesh

Strengthening managerial workflows with data-driven decision support in Sanjeevani Clinics in Madhya Pradesh, enabling better health service delivery through digital tools and analytics.

ABDM Compliant Antimicrobial Resistance Tracker

Developing a scalable, Ayushman Bharat Digital Mission (ABDM) compliant antimicrobial resistance tracker to monitor and combat AMR across healthcare facilities in India.

Understanding the Role of Digital Intervention for OCD Patients

Investigating the role of digital interventions in supporting patients with Obsessive-Compulsive Disorder (OCD), exploring how technology can improve mental health outcomes.

Sensing Social Media for Societal Good

Leveraging social media data and AI to sense public health trends, misinformation, and societal well-being indicators for evidence-based public health interventions.

Biometrics & Wearables

Design and Evaluation of a Heart Rate Variability (HRV) Measuring Arm Band

Design and evaluation of a wearable arm band for measuring Heart Rate Variability (HRV) for organ function assessment. This device enables continuous, non-invasive monitoring of physiological parameters.

National Network Project of Dr. B.R. Ambedkar Centre for Biometric Research

A national-level network project under the Dr. B.R. Ambedkar Centre for Biometric Research, focusing on advancing biometric technologies for healthcare and identity applications.

Grand Challenges India (New Funding)

Climate x Health: Tackling Vector Borne Diseases in Uttar Pradesh

Grand Challenges India funded project addressing the intersection of climate change and health by tackling vector-borne diseases in Uttar Pradesh through data-driven approaches and predictive analytics.

AI in Healthcare: Tackling AMR in Tertiary Care at AIIMS and Max Hospitals

Grand Challenges India funded project leveraging AI in healthcare to tackle antimicrobial resistance (AMR) in tertiary care settings at AIIMS and Max Hospitals, combining clinical data with advanced analytics.

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